The Laboratory headquarter is located in the municipality of Gressoney-La-Trinité (Valle d’Aosta Region). The activities of the Laboratory are carried out at the Angelo Mosso Scientific Institute, in the municipality of Alagna Valsesia (Piemonte Region), in the framework of an agreement with the Department of Neuroscience (University of Turin).

The Angelo Mosso Scientific Institute is located at 2901 meters a.s.l., in the Monte Rosa massif, and its history spans more than a century: a true sanctuary for scientific research in the high mountains.
In the Mosso Institute area, the Laboratory manages several permanent experimental areas included in the LTER Italia Network. In these areas, the effects of the climatic conditions on the dynamics of nutrients in soils and waters, as well as on plant phenology, are studied in collaboration with the CNR-IRSA (National Research Council - Water Research Institute).
In addition, a collaboration with the Meteomont Service (Italian Army) has been established since 2005. The Meteomont Service manages an automatic weather station equipped also with sensors for measuring the temperature and humidity of the soil.

The Laboratory contributes to the organisation of scientific dissemination activities at the Mosso Institute, in collaboration with the Sesia Val Grande Geopark, the Management Authority of the Protected Areas in the Sesia Valley, and the Monterosaski Ski.
At the Mosso Institute numerous teaching activities are organised in the framework of the academic courses in Forest and Environmental Sciences, and Sciences and Technologies of the Forest Systems and Territories, as well as of the IPROMO International Summer School.

The laboratory performs theoretical and applied research on:

• effects of climate change on snow conditions
• characteristics of alpine soils
• relationships between soil and alpine vegetation
• processes at the interface between soil-ice and ice-snow
• dynamics of avalanches
• impacts of cryosphere degradation on water quality
• characteristics of atmospheric deposition
• paleoenvironmental reconstruction of high elevation ecosystems.